Our Grants

We find labs where the PI has knowledge of SynGAP and/or key skills that will be essential for our quest for a therapy for our patients and we support those labs.

 
 
Dr. Holder

Dr. Holder

19/1 - Dr. Holder at Baylor

Purpose: Develop and characterize iPSC lines to support grant 19/2.

Funding: $130,000 over three years to support some of the training of a postdoctoral researcher.

Key people: Jimmy Lloyd Holder Jr, M.D., Ph.D. & Ridhima Vij Ph.D.

Status: Approved, Signed, 33% disbursed.

 
Rumbaugh Lab, Gavin in red, Nerea in stripes.

Rumbaugh Lab, Gavin in red, Nerea in stripes.

19/2 - DR. RUMBAUGH AT SCRIPPS

Purpose: To test the hypothesis that the pathogenicity of distinct SYNGAP1 variants found in patients will correlate with the extent of dysfunction in neurons derived from their own cells.

Funding: $205,500 over three years to support the training of a postdoctoral researcher.

Key people: Gavin Rumbaugh, Ph.D. & Nerea Llamosas Ph.D.

Status: Approved, Signed, 33% disbursed.

 
Dr. Huganir

Dr. Huganir

19/3 - Dr. HUGANIR at Hopkins

Purpose: Research on SynGAP animal models & to explore naturally occuring ASOs that relate to SynGAP.

Funding: $500,000 over two years to support the training of two postdoctoral researchers and the related supplies.

Key people: Richard Huganir, Ph.D.

Status: Grant agreement under discussion; 50% disbursed.