We find labs where the PI has knowledge of SynGAP and/or key skills that will be essential for our quest for a therapy for our patients and we support those labs.
19/2 - DR. RUMBAUGH AT SCRIPPS
Purpose: To test the hypothesis that the pathogenicity of distinct SYNGAP1 variants found in patients will correlate with the extent of dysfunction in neurons derived from their own cells.
Funding: $205,500 over three years to support the training of a postdoctoral researcher.
Status: Approved, Signed, 33% disbursed.
19/3 - Dr. HUGANIR at Hopkins
Purpose: Research on SynGAP animal models & to explore naturally occuring ASOs that relate to SynGAP.
Funding: $500,000 over two years to support the training of two postdoctoral researchers and the related supplies.
Key people: Richard Huganir, Ph.D.
Status: Grant agreement under discussion; 50% disbursed.